abstract |
The invention discloses a method for producing adenosine by fermentation, which relates to the deep liquid fermentation medium formula, fermentation control method and feeding method for producing adenosine by this strain, and the color purity level of the finally obtained fermentation liquid is close to 90%, It is beneficial to extract and purify the finished product of adenosine of pharmacopoeia standard. In this method, deep liquid fermentation is carried out under the formula of using high concentration glucose as carbon source and yeast extract, urea, ammonium sulfate, etc. as nitrogen source, the level of 50L fermenter can reach 11.2g/L, and the level of 1T fermenter can reach 10.5g/L L. |