http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114699445-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3039464fd5e6e1b2f369d2e9ad87f3d3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-638 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-638 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 2022-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b16c29620c5a2c3210988e71a12b5378 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701394abb5a0bdec796a76f52f5e02cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8fd4ebeb99341ae7f10942969a9cae5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_897c3d5411739899dc8ae9b135cf714d |
| publicationDate | 2022-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114699445-A |
| titleOfInvention | A kind of traditional Chinese medicine composition for treating myelodysplastic syndrome, preparation method and application thereof |
| abstract | The invention relates to a traditional Chinese medicine composition for treating myelodysplastic syndrome, a preparation method and application thereof. The traditional Chinese medicinal composition is prepared from the following raw materials by weight: 1-3 parts of realgar, 100-300 parts of dodder, 100-300 servings of Sadako, 100-300 servings of ginseng. The traditional Chinese medicine composition of the present invention has reasonable compatibility. Dodder, Ligustrum lucidum, and Radix Rhizoma "reinforcing and tonifying deficiency" are intended to aim at the positive and deficient nature of "medullary poisoning"; The four herbs complement each other, embodying the meaning of strengthening the spleen, invigorating the kidney and detoxifying, and achieving the curative effect of "supporting righteousness, removing blood stasis and toxin", which is highly in line with the connotation of TCM pathogenesis of "positive deficiency and blood stasis toxin" in MDS patients. The inhibitory effect of MDS cell proliferation is proportional to the concentration and time of the important composition of the present invention. It can enhance the autophagy of MDS cells by promoting hMOF to promote the acetylation of histone H4K16, reduce the level of oxidative stress to inhibit its cell proliferation and induce apoptosis, prevent the further transformation of MDS to AML, and thus play an anti-tumor effect and play a role in MDS. It is suitable for clinical promotion and use. |
| priorityDate | 2022-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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