| abstract |
The invention discloses an intervertebral cage formed by gradient materials, a preparation method and application thereof. The cage includes an inner core part, an outer layer part and a bone graft part; the inner core part of pure PEEK provides sufficient mechanical support, and the bioceramic/PEEK The outer part of the material and the bone graft part can improve the inertness and hydrophilicity of the PEEK material, and provide good interfacial bone growth activity. It can induce and induce the adhesion, proliferation and differentiation of bone cells, improve the fusion efficiency and long-term stability after implantation; it solves the problem that the modification of PEEK cages by the existing technology adds bone active ingredients to reduce the overall mechanical support strength and surface plating. The PEEK cage is easy to fall off when it is implanted, and the hydrophobicity of pure PEEK cage and the insufficient bone growth activity of the interface, the cage has high mechanical strength, and at the same time increases the osteogenic activity and biocompatibility of the cage. It has better clinical fusion effect. |