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filingDate 2020-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114689733-A
titleOfInvention A kind of lipalast or its preparation related substance detection method
abstract The invention discloses a high-performance liquid chromatography detection method for lipalast or related substances in its preparations, which solves the problem that most of the related substances in lipalast or its preparations cannot be detected in the prior art. The method of the invention The chromatographic conditions are as follows: use octadecylsilane-bonded silica gel as filler; use phosphoric acid, phosphoric acid aqueous solution, organic solvent, or the above-mentioned mixed solution as mobile phase, gradient elution; column temperature 20-60 ℃; detection wavelength 200- 240nm; flow rate 0.5-2.0ml/min. The method of the invention is simple, the operation is simple, at least 14 related substances in the litalast or its preparation can be measured quickly and accurately, and the product quality can be effectively ensured and the drug safety can be ensured.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115436532-A
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type http://data.epo.org/linked-data/def/patent/Publication

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