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filingDate 2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41c45407e5207055c85a6443e89bedf2
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publicationDate 2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114685576-A
titleOfInvention High-purity gastrodin unstable crystal form, its preparation method and the preparation method of gastrodin crystal form FormA
abstract The present invention provides the unstable crystal forms Form3, Form5, Form6 and Form7 of gastrodin. The X-ray powder diffraction spectrum obtained by Cu-Kα ray measurement confirms that the above-mentioned four crystal forms are all discovered for the first time, and the invention enriches the research on the crystal form of gastrodin. And the preparation process of the above crystal form is simple, the reproducibility is good, the obtained crystal form has high purity and high yield, and is easily and efficiently transformed into a stable crystal form FormA, which can be used as a high-yield preparation of high-purity gastrodin. The intermediate state of the stable form FormA. In addition, the present invention determines the most stable crystal form of gastrodin through stability research. The above research contents are obtained in the process of comprehensive research on the crystal form of gastrodin, and have certain reference value for the crystallization process and storage conditions of gastrodin.
priorityDate 2020-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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