| abstract |
The present invention provides a buprenorphine transdermal solution and a preparation method and application thereof. The solution uses buprenorphine as an active ingredient, and contains phospholipid-polyethylene glycol, a transdermal enhancer and a non-polar solvent. Addresses the problems of frequent buprenorphine administration and skin irritation in mammals, and provides a new regimen for sustained pain control. The buprenorphine transdermal solution of the invention has the effects of rapid absorption, slow release, high safety and long-acting analgesia, and can be used for postoperative analgesia in mammals. |