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filingDate 2020-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114678179-A
titleOfInvention A kind of hydrophilic magnetic solid nanosphere and its preparation method and application
abstract The present application discloses a hydrophilic magnetic solid nanosphere and a preparation method and application thereof. A hydrophilic magnetic solid nanosphere, characterized in that, the hydrophilic magnetic solid nanosphere is a core-shell structure; the shell is a hydrophilic polymer; the core is a magnetic nanoparticle wrapped with polymer I; Described polymer I and described hydrophilic polymer are connected by amide bond and/or ester bond; Described magnetic nanoparticle is selected from at least one in the material with general formula shown in formula I; Zn x Fe 3- x O 4 formula I; the value of x ranges from 0.1 to 0.9. The hydrophilic magnetic solid nanosphere is a superparamagnetic nanomaterial, which can be used as an MRI contrast agent for diagnosis, and realizes the function of magnetically responsive T1 and T2 switching imaging.
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