abstract |
The invention proposes a perindopril amlodipine bilayer tablet and a preparation method thereof, comprising a perindopril tablet layer and an amlodipine tablet layer, and the perindopril tablet layer contains arginine perindopril , microcrystalline cellulose, lactose, magnesium stearate, colloidal silicon dioxide; amlodipine sheet layer contains amlodipine besylate, microcrystalline cellulose, calcium phosphate anhydrous, magnesium stearate, colloidal silicon dioxide Silicon oxide. The preparation method of the perindopril amlodipine bilayer tablet provided by the invention not only ensures the high stability of the perindopril arginine and amlodipine besylate, but also ensures that the perindopril amlodipine bilayer Quality and efficacy of laminae. The preparation method is simple, the production cost is low, and it is suitable for industrial production. |