http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114636773-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2022-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114636773-B |
titleOfInvention | Determination method of polyethylene glycol monomethyl ether 2000 in a pharmaceutical excipient |
abstract | The application provides a method for determining the content of polyethylene glycol monomethyl ether 2000 in pharmaceutical excipients. After diluting the reference substance and the test substance with purified water, high performance liquid chromatography is used to detect polyethylene glycol in the solution of the sample to be tested. The content of alcohol monomethyl ether 2000, wherein the liquid chromatography column adopts a reversed-phase chromatography column based on silica gel and C8 filler. The detection method of the present application is explored through the liquid chromatography column, the chromatographic conditions and the dissolving solvent of the sample to be tested, so that the separation ability of polyethylene glycol monomethyl ether 2000 and the adjacent peaks in the pharmaceutical excipient to be tested is improved, and can be used The determination of polyethylene glycol monomethyl ether 2000 in polyethylene glycol-polylactic acid block copolymer and its terminal derivatives has excellent accuracy and sensitivity. |
priorityDate | 2022-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.