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filingDate 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114634651-B
titleOfInvention A kind of sterile porous collagen repair gel and preparation method thereof
abstract The invention relates to a sterile porous collagen repair gel and a preparation method thereof, comprising the following steps: preparation of phase A: adding collagen to acetic acid or hydrochloric acid at 2-8°C, mixing evenly, adding antioxidants, and mixing to obtain A phase, stored at 2-8°C; preparation of phase B: prepare a buffer solution system; sequentially add phase A and phase B into the pressure vessel, add high-pressure gas to the pressure vessel, seal the pressure vessel, sterilize by irradiation, 2 ‑8℃, open the pressure container when using, and obtain the sterile porous collagen repair gel. The method of the present invention adds a closed-cell structure to the collagen gel by changing the solubility of the gas in water by pressure, so as to better induce tissue regeneration. The collagen of the present invention has a specific buffer, temperature and pH value Under the environment, the collagen solution can be transformed from liquid state to gel state, and has a good clinical application prospect.
priorityDate 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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