http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114632087-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ea95b89ec0cea21268eb3e804df6f68 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2022-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_298a551162cc1ed25dd763d0bbea3c62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6af535f5b1ff06b72629b083de770e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dbca3b8bda432c2bd532bab9eda1323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d43963b37f1d31650d3f052d172d0708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9933ac0bbafc29719d2a74d8016fe56 |
| publicationDate | 2022-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114632087-A |
| titleOfInvention | Application of NMN in the preparation of drugs for preventing and treating vascular endothelial cell aging, vascular aging and vascular atherosclerosis |
| abstract | The invention discloses the application of NMN in the preparation of medicines for preventing and treating vascular endothelial cell aging, vascular aging and vascular atherosclerosis. Described in more detail, the NMN can be used to improve the senescence of vascular endothelial cells induced by any one of the above means of interleukin-6, oxidized low-density lipoprotein and passage replicating; the NMN can also be used to improve the senescence of vascular endothelial cells caused by Western high-fat diet and Vascular aging and atherosclerosis induced by natural aging models; specifically, an effective amount of activity is included in the preparation of drugs, drug mixtures or pharmaceutical compositions for preventing and treating endothelial cell aging and/or vascular aging and/or atherosclerosis The NMN of the ingredients and a pharmaceutically acceptable carrier are sufficient. Through in vitro cell experiments and in vivo animal experiments, the present invention proves that NMN can delay the aging of vascular endothelial cells, delay the process of vascular aging, and inhibit the occurrence of vascular degenerative disease atherosclerosis. |
| priorityDate | 2022-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.