http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114624432-A

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filingDate 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08b51b0435511b844a3dd1e1804dda2c
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publicationDate 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114624432-A
titleOfInvention A kind of acridinium ester-labeled antibody and its preparation method and application
abstract The invention relates to the technical field of chemiluminescence immunoassay, and discloses an acridine ester-labeled antibody and a preparation method and application thereof. The acridine ester-labeled antibody includes acridine ester, polyamino Auricularia polysaccharide AF1 and an antibody; the polyamino Auricularia polysaccharide AF1 is the Auricularia polysaccharide AF1 grafted with multiple amino groups; the acridine ester is connected to the polyamino group On the amino group of black fungus polysaccharide AF1; the antibody is linked with polyamino black fungus polysaccharide AF1. The acridinium ester-labeled antibody of the present invention utilizes the polyaminosaccharide polysaccharide AF1 to connect the acridine ester and the antibody, which can increase the binding amount of the acridine ester on the antibody, thereby improving the detection sensitivity. The binding between the pyridine ester-labeled antibody and the antigen causes excessive obstacles, which is beneficial to the improvement of detection sensitivity.
priorityDate 2021-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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