Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_676a6f61f0e88453b7aa09930bfa9c6e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0631 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y306-04013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0693 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate |
2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_850ab88822c0a69dd13912bfafb48671 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_631f35cac4fb5e391ed62f9dac971e99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26bbe0fc642adc87a8455dfebcd7633c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfc320671c5288e0724a4e64f85513ce |
publicationDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114621994-A |
titleOfInvention |
Application of a drug for treating or preventing breast cancer and human DDX46 gene |
abstract |
The invention is applicable to the field of biotechnology, and provides the application of human DDX46 gene in screening breast cancer therapeutic drugs; the application of human DDX46 gene in the preparation of breast cancer diagnostic drugs; the DDX46 gene regulates breast cancer proliferation and differentiation by regulating c-Myb expression and reducing ; Application of DDX46 gene knockdown cells in the preparation of drugs for preventing or treating breast cancer. The present invention finds that knocking down DDX46 significantly reduces the proliferation ability of breast cancer cells, induces cell cycle arrest and apoptosis of breast cancer cells, and reduces the invasion and migration ability of breast cancer cells. Mechanisms regulating the proliferation and differentiation of breast cancer. |
priorityDate |
2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |