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filingDate 2022-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114621994-A
titleOfInvention Application of a drug for treating or preventing breast cancer and human DDX46 gene
abstract The invention is applicable to the field of biotechnology, and provides the application of human DDX46 gene in screening breast cancer therapeutic drugs; the application of human DDX46 gene in the preparation of breast cancer diagnostic drugs; the DDX46 gene regulates breast cancer proliferation and differentiation by regulating c-Myb expression and reducing ; Application of DDX46 gene knockdown cells in the preparation of drugs for preventing or treating breast cancer. The present invention finds that knocking down DDX46 significantly reduces the proliferation ability of breast cancer cells, induces cell cycle arrest and apoptosis of breast cancer cells, and reduces the invasion and migration ability of breast cancer cells. Mechanisms regulating the proliferation and differentiation of breast cancer.
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