| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43b2659e07d0fb9f77820066701b56c0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0629
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0691
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0656
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0688 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-071
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_240fd2fbf06db6bfec30fb4322d8c85e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21f6f525ce00d66d45e6858f98691f77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16b6e040c0bfdeb5ad75c7ceaac8e4ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23aeaf0468a5fe6538e8dcf095c46b0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d25f48fdeb32b3f96d483be0a435c3a |
| publicationDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114621912-A |
| titleOfInvention |
A method for constructing biological barrier models based on nanowire mesh and organ-on-a-chip technology |
| abstract |
The present invention provides a novel bionic basement membrane based on nano-mesh technology, and a method for constructing a biological barrier model based thereon. The new biomimetic basement membrane is made of gelatin as the main component, combined with micro-nano processing technology and electrospinning technology, and has good biocompatibility, nano-scale film thickness, high porosity and flexible controllability. One or more nanowire meshes are combined to construct an in vitro biological barrier model, which is then integrated with a microfluidic chip to develop a new in vitro evaluation system for the ability of drug penetration through the bionic basement membrane and dynamic microenvironment simulation. It is expected to bring further changes to the development of new drugs. |
| priorityDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |