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filingDate 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114621467-B
titleOfInvention A kind of sterile self-curing collagen repair gel and preparation method thereof
abstract The invention relates to a sterile self-curing collagen repair gel and a preparation method thereof. The method comprises the following steps: preparation of phase A: adding collagen to acetic acid or hydrochloric acid at 2-8° C., mixing evenly, adding anti-aging Oxidant, mix to obtain phase A, and store at 2-8 °C; preparation of phase B: prepare a buffer solution system, the buffer solution system is a phosphate buffer solution, a Tris-HCl buffer solution, and a sodium barbital-hydrochloric acid buffer solution. One; Phase A and Phase B are respectively loaded into different containers, sterilized by irradiation at the same time, stored at 2-8° C., and Phase A and Phase B are mixed during use to obtain the sterile self-curing collagen. Repair gel. The gel prepared by the method of the present invention can be provided in a sterile state, can still maintain the gel-forming performance after sterilization, and can quickly form a gel in a short period of time after contacting the body fluid environment. Require.
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