| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_88b2da25411502d4b64462b17a418df5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0097
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5176
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-00 |
| filingDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8f040f384e2e8c289e0e8f08eea74be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c65edc95a7b8aa0a2818a593f79102ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e41cf242008d132ddbde7722ebd0c2ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9968f2e5ab5badb86be6f155e1508562
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7a25324ca06ab1993864580b1827dd3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ee0cfe117d180df83b352328502f87e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d95954be7f8c98fdb7a3940263539651 |
| publicationDate |
2022-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114617857-A |
| titleOfInvention |
Application and preparation method of bacterial perforating toxin-responsive erythrocyte membrane nanovesicles in broad-spectrum antibacterial |
| abstract |
The invention discloses an application of bacterial perforating toxin-responsive erythrocyte membrane nanovesicles in broad-spectrum antibacterial and a preparation method thereof. In the application, the erythrocyte membrane nanovesicles are encapsulated with perfluorooctane to form RBCM@PFC. Before injecting oxygen or nitric oxide. The preparation method has the following steps: 1. obtaining red blood cell membranes; 2. adding red blood cell membranes to perfluorobromooctane and ultrasonically treating them to obtain RBCM@PFC suspension; 3. filling the RBCM@PFC suspension with nitric oxide to obtain RBCM@PFC‑NO Finished product, or add photosensitizing reagent IR780 to RBCM@PFC suspension for ultrasound, and fill with oxygen to obtain RBCM@PFC‑IR780‑O 2 finished product. The invention can realize broad-spectrum antibacterial resistance against drug resistance, overcome the problem that antibiotics are easy to produce drug resistance, and can combine exotoxin neutralization strategy and active gas treatment to achieve effective removal of bacterial infection. |
| priorityDate |
2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |