http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114605665-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2487-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2489-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2305-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-35 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L87-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 |
filingDate | 2022-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114605665-B |
titleOfInvention | A functional double supramolecular interaction hydrogel, preparation method and application |
abstract | The invention discloses a functional double supramolecular interaction hydrogel, a preparation method and an application. The hydrogel is obtained by the reaction of fluorescent protein-polymer conjugates, nanobody polymers and α-cyclodextrin, and the fluorescent protein-polymer conjugates are composed of green fluorescent protein GFP and GFP modified with reactive sites. The sequence of the green fluorescent protein GFP modified with the reaction site is shown in SEQ ID NO:1, and the sequence of the nanobody multimer is shown in SEQ ID NO:2. The hydrogel of the present invention achieves very high elastic modulus and viscous modulus through double supramolecular interaction, and has no toxic and side effects, and can be used for biological materials; it can change shape, can effectively recruit and activate macrophages, It shows the prospect of tumor immunotherapy; it can be used for cell imaging, and has excellent application value and potential. |
priorityDate | 2022-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 403.