http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114601844-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da87b56482160b96a1b516ccc5bd6a08 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 |
| filingDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be965c1793d665974abcbfff5ab8c059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eea360432ec789e93ce7a674f13883d6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a2356944b85aa64ad5147c542c9c321 |
| publicationDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114601844-A |
| titleOfInvention | Application of an Hsp70 inhibitor in the treatment of breast cancer |
| abstract | The invention discloses the application of an Hsp70 inhibitor in the treatment of breast cancer, relates to the technical field of medicine, and solves the technical problem of chemotherapy resistance in a large number of patients in the breast cancer treatment process in the prior art. The application of the Hsp70 inhibitor of the present invention in the treatment of breast cancer, the Hsp70 inhibitor is Apptozole or VER-155008, and the Hsp70 inhibitor is used to reverse the drug resistance of breast cancer cells caused by high expression of DNAJC12 in the treatment of chemotherapy drugs sex and promote ferroptosis in breast cancer cells. The application of the Hsp70 inhibitor of the present invention in the treatment of breast cancer, the Hsp70 inhibitor can reverse the drug resistance of breast cancer cells in the treatment of chemotherapy drugs caused by the high expression of DNAJC12, and promote the ferroptosis of breast cancer cells, so that the Improve the therapeutic efficacy of chemotherapy drugs and benefit patients. |
| priorityDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 99.