| abstract |
The present invention provides an amide compound capable of improving the yield and purity of a polyoligonucleotide, a glycoside compound as an intermediate thereof, and a method for producing a polynucleotide using the amide compound. The present invention also provides the amide compound of formula (1) and the glycoside compound of formula (10) capable of improving the yield and purity of polyoligonucleotides (in formulas (10) and (1), B a , R a , and R b ) , R c , G 1 , G 2 and G 3 are as defined in the specification, and R is represented by the following formula), and a method for producing a polynucleotide using the amide compound. |