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filingDate 2022-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114588265-A
titleOfInvention An immunomodulator for the treatment of colorectal cancer lung metastases and a composition for prediction and detection thereof
abstract The present invention relates to an immunomodulatory agent for the treatment of colorectal cancer lung metastasis and a composition for prediction and detection thereof. The immunomodulatory agent includes substances that inhibit the deletion of Bmal1 gene, and/or substances that inhibit the deletion of Per1 and Per2 genes, Compositions for predicting or detecting lung metastases from colorectal cancer include reagents for the detection of Helicobacter Helicobacter and Bacteroides lachnoclostridium, and/or reagents for the detection of the bile acid taurocholic acid. The invention affects the development process of colorectal cancer lung metastasis by regulating the tumor immune microenvironment, and predicts the risk of colorectal cancer lung metastasis by detecting the abundance of intestinal bacteria and its metabolites.
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