http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114574553-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_384fab648e60871d317c33aea968e23c |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-682 |
filingDate | 2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41c3a8c1acdc1d78e0dabd7696ecb76d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fce42a00c49bf0762b67df9d9cc8a84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cc4947b72200e488c5e89d4075b70f3 |
publicationDate | 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114574553-A |
titleOfInvention | A kind of carbon dot-nano gold spherical nucleic acid and its preparation method and application |
abstract | The invention discloses a carbon dot-nano gold spherical nucleic acid and a preparation method and application thereof. The carbon dot-nano gold spherical nucleic acid takes nano gold as a core, and the surface is coupled with a DNAzyme chain and a substrate labeled with carbon dots at the end. When the carbon dot-nano gold spherical nucleic acid prepared by the present invention detects exosome miRNA, in the presence of metal ions, target miRNA recognition triggers DNAzyme walking to generate fluorescence; fluorescence spectrophotometer is used to measure the fluorescence signal of CDs after walking, Realize the detection and analysis of miRNA. At the same time, the present invention is based on two-color CDs-SNA for the detection of two exosome miRNAs, uses DNAzyme to mediate CDs fluorescence signal amplification, and realizes highly sensitive detection of miRNAs; uses two-color CDs-SNA to realize simultaneous detection of miRNAs, which is exosome The precise detection of miRNA provides a new method. |
priorityDate | 2021-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.