abstract |
The invention discloses a lactone compound and a cerium-catalyzed synthesis method of the lactone compound. The synthesis method of the present invention comprises the following steps: under the irradiation of visible light, under the atmosphere of oxygen, in the presence of a photocatalyst and a cerium catalyst, the cyclic ketone compound containing the structural fragment shown in formula II is subjected to the following formula in a solvent The cyclization reaction is carried out to obtain the lactone compound containing the structural fragment shown in formula I. Starting from simple and readily available raw materials, the method can conveniently and quickly synthesize various mid-ring and macrocyclic lactones, and has the advantages of simple operation, economical application and environmental protection. |