http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114569903-A

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filingDate 2022-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b561d5bcd737a43bb7448c572409c20c
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publicationDate 2022-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114569903-A
titleOfInvention In vitro non-invasive therapeutic apparatus for pulsed ultrasound synergistic drug and operation method thereof
abstract The invention belongs to the technical field of medical equipment, and specifically discloses a pulsed ultrasonic synergistic drug in vitro non-invasive therapeutic apparatus and an operation method thereof, including an ultrasonic generation system, a drug monitoring system and a drug delivery system. The ultrasonic generation system includes an ultrasonic generator and an ultrasonic wave. The transducer, the ultrasonic transducer has a low-frequency range and a high-frequency range; the drug monitoring system is a reflective fluorescence imaging system, which detects the drug-loaded nanoparticle by collecting the fluorescent photons reflected by the drug-loaded nanoparticles marked with fluorescent substances in the skin tissue. The fluorescence intensity of the drug nanoparticles is used to monitor the enrichment degree of the drug in the lesion tissue of the treatment area; the drug delivery system is combined with the drug monitoring system to realize the precise and controlled release of the drug. This therapeutic apparatus integrates ultrasonic drug penetration and sonodynamic therapy, and realizes non-invasive in vitro treatment of tuberculosis lesions and precise drug delivery, high-efficiency controlled release, and high-efficiency sterilization through ultrasonic synergy with drugs, preventing the formation of drug-resistant tuberculosis bacteria or reversing drug resistance. .
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Total number of triples: 33.