| abstract |
The invention relates to the technical field of biomedical materials, and specifically discloses an artificial periosteum containing quercetin and magnesium oxide, wherein the artificial periosteum is a nanofiber membrane containing magnesium oxide nanoparticles and quercetin. It is also disclosed that the preparation method of the artificial periosteum includes the following steps: 1) Dissolving degradable polymer materials, magnesium oxide nanoparticles and quercetin in an organic solution, stirring and dissolving at room temperature to obtain an electrospinning solution: 2) The electrospinning solution is prepared into artificial periosteum by electrospinning method. And discloses the application of the artificial periosteum in the preparation of periosteal tissue repair material. The artificial periosteum prepared by the invention has the functions of promoting cell migration, promoting bone and promoting blood vessel formation, can accelerate bone regeneration in the bone defect area, can induce cell adhesion, proliferation, differentiation and mineralization, and is conducive to the formation of local new blood vessels, and can better to meet clinical needs. |