| abstract |
The invention belongs to the technical field of bioengineering, and discloses a method for producing EPA and DHA by fermentation of Schizochytrium spp. The method uses Schizochytrium spp. as a production strain, adds ensidipine to a fermentation medium, and fermented to produce more saturated fatty acid. The invention increases the content of EPA and DHA in the fermented product of Schizochytrium by activating part of the ELO/DES pathway of Schizochytrium, and adopts the engineering bacteria EDG of Schizochytrium as the production strain, so that the content of EPA in the fermentation product is increased by 8.73 times, and the DHA content in the fermentation product is increased by 8.73 times. The content is increased by 1.15 times. |