http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114558176-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 |
filingDate | 2022-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114558176-B |
titleOfInvention | A chitosan-chondroitin sulfate nanoparticle, a drug-loaded joint lubricant |
abstract | The invention provides chitosan-chondroitin sulfate nanoparticles and a drug-loaded joint lubricant, belonging to the technical field of joint lubricants. In the present invention, chitosan has advantages such as good biocompatibility, blood compatibility, biodegradation and human body metabolism, can be used as a safe and reliable drug carrier for the treatment of arthritis, and chitosan itself has good Bactericidal properties. Chondroitin sulfate contains a large number of hydrophilic sulfonic acid groups, which can endow chitosan nanoparticles with excellent water lubrication performance, so that chitosan-chondroitin sulfate nanoparticles have a good anti-friction effect; chondroitin sulfate itself has cartilage repair It can promote the growth of cartilage and lay a good foundation for the drug-loaded treatment and repair function of joint lubricants. Because chitosan nanoparticles have a soft network structure microscopically, when they are used as drug carriers, the drugs encapsulated in them can be released slowly at the damaged joint interface, showing excellent stress-induced sustained release effect. |
priorityDate | 2022-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.