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filingDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64db1adcdef41de6f865a0549018e24a
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publicationDate 2022-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114558144-A
titleOfInvention Preparation and application of a novel black fungus polysaccharide-coated carbon nanotube-loaded doxorubicin material
abstract The invention discloses the preparation and application of a novel black fungus polysaccharide-wrapped carbon nanotube-loaded doxorubicin material, and belongs to the field of nanomaterials. The material of the present invention is obtained by mixing the black fungus polysaccharide solution, the carbon nanotube solution modified by acid oxidation, and the doxorubicin solution, and then stirring and reacting. The dispersibility and stability of doxorubicin, the material has excellent photothermal and pH-responsive slow-release effects, which greatly reduces the toxic and side effects of normal cells and improves the anti-tumor efficacy. The invention solves the problems of poor effect, short half-life, high toxicity and high dosage of traditional chemotherapeutic drugs, and has great significance for the research and development of new anti-tumor drugs and the development of new anti-tumor combination means.
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