| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_625600b152a98a1d56beaeff2fb05638 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-06 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70539
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0634
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2020-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dcfbd4babbc45523a2318067966bc40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69a3e8bd6ebe9e14f4f83a5786af2ccd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58374d14b048e50ae131924e14c45a73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_053e6e947e7cb2738012d45c06f9dcb4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2178a18349d643e33a724f52c241661e |
| publicationDate |
2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-114555789-A |
| titleOfInvention |
engineered immune cells |
| abstract |
The present invention relates to engineered immune cells comprising: (i) a target-binding polypeptide comprising a target-binding domain and a first protein-interacting domain; and (ii) a localization polypeptide comprising binding to a first protein-binding domain of the second protein-interacting domain and the intracellular retention signal. When a target-binding polypeptide binds to its target protein and localizes the polypeptide, the expression of the target protein on the cell surface is reduced or eliminated as the target protein remains in the intracellular compartment. |
| priorityDate |
2019-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |