http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114544930-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf80d252c03a54eff79c66678fdee30a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-04 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-28009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-30 |
| filingDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fea1f982cc3cbf3f289a83986f6168c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e33eddde21b757658dcb2c6763b518 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_628c2a1bbf15f004f33d8da84d26e58f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_759af0652ff83f412e078228678f2422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3ff2fa507dbaaec1207f9626307699f |
| publicationDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114544930-A |
| titleOfInvention | A method based on electroporation of cell membrane-coated magnetic beads for fishing active ingredients of traditional Chinese medicine and its application |
| abstract | The invention discloses a method based on electroporation for cell membrane-coated magnetic beads to fish for active ingredients of traditional Chinese medicine. The method includes: 1. using coating and modification to synthesize Fe 3 O 4 @BSA-RDG magnetic nanoparticles; 2. using electroporation Preparation of complete macrophage membrane-coated nano-magnetic beads by perforation; 3. Active ingredients of fishing traditional Chinese medicine; the invention also discloses the application of the above method in the active ingredients of fishing aconite. In the present invention, Fe 3 O 4 @BSA-RGD magnetic nanoparticles with good biocompatibility and membrane targeting are synthesized, co-cultured with target cell macrophages, and then electroporated to construct a complete macrophage membrane-coated nano-magnetic The bead system ensures the structural integrity of the cell membrane and the outer surface faces outward. Compared with the traditional coating method, it does not distinguish the outer/inner surface orientation of the membrane, which increases the number of targets on the surface of the fishing carrier and improves the accuracy and sensitivity of the screening of active ingredients in traditional Chinese medicine. ; The application of the present invention realizes the fishing of anti-inflammatory active components in aconite. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115245500-A |
| priorityDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.