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filingDate 2022-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae06380aa1f8141b46117d6d6d46f8a6
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publicationDate 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114540498-A
titleOfInvention A DNA methylation-based classification device for invasive gliomas
abstract The invention relates to the technical field of biomedicine, in particular to a classification device for invasive glioma based on DNA methylation. The device includes a detection module, a classification module and an information display module; by measuring the degree of methylation of CpG islands To predict whether glial cells are cancerous and the degree of canceration, and classify gliomas, real-time quantitative methylation-specific PCR is not only sensitive and accurate, but also can detect DNA in formalin-soaked specimens. Methylation status, so real-time quantitative methylation-specific PCR has the potential to be used for the diagnosis of glioma. Since miRNA can exist stably in serum and is easy to obtain, it has the potential to become a molecular marker for early diagnosis. The content of miR-25 and miR-223 can be used as diagnostic markers for patients with non-small cell lung cancer; after screening specific glioma miRNA markers and extracting DNA from the patient's blood, the expression level of miRNA can be detected by PCR. Glioma can be diagnosed early.
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