http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114539092-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132fb49024f569917a25da8a66e412e5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-34 |
| filingDate | 2022-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c91e62f9ec1fdd79e61b35a4e66d80bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b9c5683d43f6087340bfbafe75c70fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfd081620a1d0043bb2ca5db58c2735a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_503d2bee4e23a669c6e2bdb31f6d9838 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52f1d2fa85c27d169a7bd28371708e68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c07d8e682dbe83d8fa6aab5ebb6ec40f |
| publicationDate | 2022-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114539092-A |
| titleOfInvention | A kind of oat gluten amide alkaloid and preparation method thereof and application in the preparation of antipruritic products |
| abstract | The invention relates to the technical field of medicinal chemistry, and specifically discloses an avena gluten amide alkaloid, a preparation method thereof, and an application in the preparation of an antipruritic product. The avena gluten amide alkaloid has the structure shown in formula I or formula II. The preparation method of the avena gluten phenolamide alkaloid specifically comprises the following steps: taking the reaction substrate caffeic acid analog, adding an organic solvent, adding 4-(2-aminoethyl) phenol and triethylamine under stirring, and 3 HATU was added after ~6 minutes; after the addition of materials, the reaction was continued at room temperature for 3 to 6 hours, TLC monitored the disappearance of the reaction raw materials; the stirring was stopped, the reaction system was evaporated under reduced pressure to remove the solvent, and the residue was purified by silica gel column chromatography to obtain the Avena glutenamide alkaloids. Research shows that the avena gluten amide alkaloid or the composition thereof has excellent antipruritic effect; therefore, the avena gluten amide alkaloid or the composition thereof can be used to develop antipruritic products. |
| priorityDate | 2022-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.