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filingDate 2022-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114518456-A
titleOfInvention A method and kit for predicting the efficacy of tumor immunotherapy by DIAPH1 protein
abstract The invention provides a method and kit for predicting the efficacy of tumor immunotherapy by using DIAPH1 protein. The method includes the following steps: using DIAPH1 protein as a molecular marker, using DIAPH1 monoclonal antibody or polyclonal antibody, combined with immunohistochemical reagents, and detecting The expression level of DIAPH1 protein in tumor tissue, and the efficacy of immunotherapy for patients is predicted according to the expression level of DIAPH1 protein in tumor tissue. The present invention uses DIAPH1 protein as a protein molecular marker for judging the efficacy of immunotherapy in patients. Compared with PD-L1 expression, DIAPH1 expression has a more significant predictive value for immunotherapy, and has important guiding significance for whether a patient is suitable for immunotherapy treatment.
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