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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869
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filingDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114517229-B
titleOfInvention Application of serum exosomal RNA in the preparation of reagents for screening or early diagnosis of macrosomia in gestational diabetes
abstract The invention discloses the application of serum exosomal RNA in the preparation of reagents for screening or early diagnosis of macrosomia caused by gestational diabetes. Application of reagents for detecting mRNA GDF3 and lncRNA AC006064.4 derived from serum exosomes in the preparation of reagents for screening or early diagnosis of high-risk pregnant women with gestational diabetes mellitus. The present invention uses the expression levels of mRNA GDF3 and lncRNA AC006064.4 derived from serum exosomes, combined with the age of pregnant women, fasting blood sugar and 2h blood sugar, the specificity of early diagnosis of gestational diabetic macrosomia can reach 1.00, and the sensitivity can reach 0.55. Therefore, the reagents of the above two indicators can be used to assist in the early diagnosis of macrosomia in gestational diabetes, and provide support for clinicians to accurately predict the risk of macrosomia and take more individualized prevention and treatment programs in a timely manner, thereby minimizing adverse pregnancy outcomes .
priorityDate 2022-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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