Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5c96edff41cc07f2a66249e75b73f6e3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-999 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0604 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-073 |
filingDate |
2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bad88da630920cee32164a1415a356b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69627b50e9bf72e210925aca954254e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9c038c31d5b396535d6816e464c0fdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe23825a7771f13ac5a0c2f90ccf2dcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_367b6c49bef208ccb6abc337a91e26a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a4396fabb87ff80599858c1caf33129 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0881081ae0c1966ef992d245a5b66270 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8296d2814255f12d46504571acd156f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ea6d5d10c62d5c1cfddfa9048c6579c |
publicationDate |
2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114507636-A |
titleOfInvention |
A method for improving the efficiency of animal embryonic development |
abstract |
The invention relates to a method for promoting the in vitro development of pre-implantation embryos and improving the efficiency of embryo transfer. The method comprises culturing the embryos in a culture solution containing α-ketoglutaric acid, or adding α- Ketoglutaric acid. The addition of α-ketoglutarate to the in vitro embryo culture medium can improve the blastocyst rate, hatch blastocyst rate, the number of cells in the blastocyst inner cell mass and the proportion of the total number of cells, thereby significantly improving the embryo transfer rate. pregnancy rate. The method for promoting the in vitro development of embryos provided by the invention has simple and easy operation process and low cost, and provides an effective method and a new idea for further improving the in vitro culture and development of mammalian embryos and the development of assisted reproductive technology. |
priorityDate |
2018-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |