http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114507591-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5e4bec76b54637292b01f288e7e03e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d4822dfff5709a719ddfb821a88a04d7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
| filingDate | 2021-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_257ec13215d20d6b2a3e63c887b747d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8929055bdec1b0b1633dd7a1dfb60681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76277c663ac16b65715aa017a4152818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7e27b026666cd168a22d36560cc6ef6 |
| publicationDate | 2022-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114507591-A |
| titleOfInvention | A microfluidic chip |
| abstract | The invention relates to a microfluidic chip, which is used for simultaneously detecting CAR-T cells and various cytokines in the peripheral blood of patients, comprising: a valve layer, a pipeline layer and a basal layer sequentially connected from top to bottom; the pipeline layer includes: : a sample mixing module, a CAR-T cell capture detection module, a concentration gradient generation module, a cell filtration module, and a cytokine detection module connected in sequence; the microfluidic chip of the present invention can treat cancers receiving CAR-T cell therapy. Simultaneous detection of CAR-T cells and cytokines in the peripheral blood of patients eliminates the need to transfer whole blood samples to a flow cytometer for detection. The microfluidic chip can detect samples of different concentrations at the same time, effectively improving the The detection range, the microfluidic chip reaction pipeline is a closed environment, which provides a relatively stable detection environment for the detection of CAR-T cells and cytokines; and the blood sample volume required for the detection is 50 microliters, which is more than the existing detection technology. Fewer samples are required and the corresponding reagents are used less. |
| priorityDate | 2021-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.