abstract |
The present invention relates to a complex, in particular to a polypeptide that specifically binds to the non-canonical MHC protein CD1d and modulates CD1d-mediated biological functions. The invention particularly relates to such complexes and polypeptides comprising or consisting of at least one single domain antibody, wherein the at least one single domain antibody specifically binds to CD Id. The invention also provides methods and uses of using such complexes, polypeptides and/or single domain antibodies. |