http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114480501-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 |
filingDate | 2022-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-114480501-B |
titleOfInvention | A kind of human antibody expression plasmid and its construction method |
abstract | The invention discloses a human antibody expression plasmid system. The human antibody expression plasmid system comprises a human antibody heavy chain expression plasmid and a human antibody light chain expression plasmid. The human antibody heavy chain expression plasmid contains a heavy The homologous arm recombination sequence of the chain variable region, the heavy chain coding gene of the human source antibody is carried by itself and is integrated into the homologous arm recombination sequence identical to the homologous arm recombination sequence of the heavy chain variable region through homologous recombination In the human antibody heavy chain expression plasmid, and in the human antibody light chain expression plasmid containing the homologous arm recombination sequence of the light chain variable region, the human antibody light chain coding gene is carried by itself, and is combined with The same homologous arm recombination sequence of the light chain variable region homologous arm recombination sequence is integrated into the human antibody light chain expression plasmid through homologous recombination. The human antibody expression plasmid system provided by the present invention has the advantages of saving time, high efficiency and high accuracy when used for the preparation of human antibody. |
priorityDate | 2022-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.