| abstract |
The invention relates to the technical field of material separation and purification, and specifically discloses a method for preparing curcumin compound monomer crystals and its application. In the method for preparing curcumin-based compound monomer crystals of the present invention, the curcumin-based compound monomer crystals are bis-demethoxycurcumin crystals, which include the steps of extracting raw materials, evaporating crystallization and cooling crystallization; The raw material is a mixture of curcumin monomer, demethoxycurcumin and double demethoxycurcumin, and the extraction does not adopt a chromatographic process. The content of the double demethoxy curcumin in the double demethoxy curcumin crystal obtained by the method is not less than 90%, the product appearance is orange-red, the crystal habit is spherulite or spheroid, and the particle size is uniform; and the process is simple, The operation is convenient, suitable for industrial production, and the product yield can reach more than 60%. |