http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114454392-A

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filingDate 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a19aae37d5dc17c35f8cd58d3712e6df
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publicationDate 2022-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114454392-A
titleOfInvention Microneedle master mold, negative mold and preparation process thereof, microneedle patch and preparation process thereof
abstract The invention belongs to the technical field of microneedles, and specifically discloses a microneedle master mold, a female mold and a preparation process thereof, a microneedle sticker and a preparation process thereof. The microneedle master mold includes a PDMS forming groove and a defoaming film, and a plurality of microneedle protrusions are arranged in an array in the PDMS forming groove; and the defoaming film is attached above the PDMS forming groove. When using the master mold to prepare the negative mold, the PDMS mixed solution is added to the PDMS forming tank, and the defoaming film is attached to the top of the PDMS forming tank to seal the PDMS mixed liquid in the PDMS forming tank, so that the negative mold can be planarized without bubbles. shaping. In the invention, the negative mold obtained by re-engraving the master mold has good integrity, and polymer microneedles of any shape can be prepared; the microneedles produced by the negative mold have the advantages of precise administration, controllability and stability, simple production, material saving and low cost. The characteristics of flexible transformation can effectively improve the yield and preparation efficiency, and reduce costs.
priorityDate 2022-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 32.