abstract |
The invention discloses a human granulosa cell line derived from ovary and a preparation method and application thereof. The human granulosa cell line is human granulosa cell hGC-YH derived from ovary, which has been deposited in the General Microbiology Center (CGMCC) of the China Microorganism Culture Collection on December 3, 2021, and its deposit number is CGMCC No.45005. The human granulosa cell line described in the present invention has high adherence rate, high uniformity, high survival rate and strong stability, and is suitable for studying the mechanism of oocyte maturation, the pathogenesis of polycystic ovary syndrome, the protection mechanism of female reproductive function, and screening Good experimental material for gonadotropin therapy drugs. |