http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114437154-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a50b4c9d3ea196fec12d8b31e1343d4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 |
| filingDate | 2022-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b36e1819f69025af40b2677adabfff2a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e012d97b03d3cbb143885689f532ae4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5709c34fa56eb6035861ce36765549c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d6ddced6101d82ea45a5f1954e13e99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_316bbea5fbf3ac61f71c128345745d88 |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114437154-A |
| titleOfInvention | A kind of ketolide derivative containing quinolone and its preparation method and application |
| abstract | The invention provides a ketolide derivative containing a quinolone and a preparation method and application thereof. The structural feature of the ketolide derivative is that the 3-position carbonyl group replaces the 3-O-cladinose of the original clarithromycin, Avoid 3‑O‑cladinose-induced bacterial resistance. At the same time, a side chain of suitable length is drawn from the nitrogen atom of the 11, 12-position cyclic carbamate functional group of the ketolide derivative, and its end is connected with various quinolones. It is verified by experiments that the ketolide derivative retains the antibacterial activity against sensitive bacteria, and has excellent antibacterial activity against constitutively resistant bacteria with high resistance levels. |
| priorityDate | 2022-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 132.