http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114437030-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_180f7c58622a8c001dcd79281ef831c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2022-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5edb23c0cdc572d48e7d2421255bcdc5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_619a09427dc14379d090b095d7eecce4 |
| publicationDate | 2022-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114437030-A |
| titleOfInvention | Preparation of Loratadine Intermediate Double Bond Isomer Impurities |
| abstract | The invention discloses a method for preparing a loratadine intermediate double bond isomerization impurity, which comprises the following steps: extracting hydrogen with a strong base, then heating for reaction, re-protonation to obtain a product, and after hydrogen extraction, it needs to heat up and undergo thermodynamic reaction to obtain a target The product, at low temperature, is kinetically controlled to generate LLTD‑1, so it is necessary to further heat up the reaction to obtain impurities after hydrogen extraction at low temperature. The method is simple and easy to implement, and the obtained product has high purity. |
| priorityDate | 2022-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.