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filingDate 2021-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66e82868bee0664ad2c9bbb4d72bb0ec
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publicationDate 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-114414802-A
titleOfInvention Early diagnosis kit based on four combined detections of liver cancer and application
abstract The invention belongs to the technical field of immunodetection, and discloses a liver cancer tumor marker based on four liver cancer tumor markers: a combined detection kit of aldo-keto reductase 1B10(AKR1B10), abnormal prothrombin (DCP), Alpha Fetoprotein (AFP) and alpha fetoprotein heteroplasmon (AFP-L3). The kit comprises: streptavidin magnetic beads; biotin labeling of AKR1B10, DCP, AFP antibodies; acridinium ester labels AKR1B10, DCP, and AFP antibodies; LCA magnetic beads, a cleaning solution and an eluent; AKR1B10, DCP and AFP calibrator and quality control product. And analyzing and judging the risk of the potential development of the subject to the liver cancer by simultaneously detecting the contents of the four tumor markers in the serum of the subject. The invention adopts the combined detection of four tumor markers to improve the sensitivity and specificity of the early diagnosis of the liver cancer and provides more reliable basis for the clinical diagnosis of the liver cancer.
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