http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114414691-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aaadcd534c1edeab62f85ec7991cb759 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-74 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-74 |
| filingDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd724ec7926f6cfeebc04b29d814cedc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_088632b3788ce0405903aaaee9a329e5 |
| publicationDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114414691-A |
| titleOfInvention | On-line solid-phase microextraction high-performance liquid chromatography coupled detection method for a new type of benzodiazepines |
| abstract | The invention discloses an online solid-phase microextraction high-performance liquid chromatography combined detection method for benzodiazepine new drugs. The invention uses a covalent organic framework surface functionalized solid-phase micro-extraction monolithic column as the solid-phase micro-extraction column, and combines the in-tube solid-phase micro-extraction-high performance liquid chromatography online combined system to establish a new benzodiazepine drug On-line solid-phase microextraction coupled with high-performance liquid chromatography for detection. The present invention utilizes the hydrophobic interaction and π-π stacking effect between the covalent organic framework on the surface of the monolithic column and the benzodiazepine compounds, thereby realizing the efficient enrichment of trace benzodiazepine compounds in actual body fluid samples and beverage samples. Integrated extraction and high-sensitivity on-line detection. The method of the invention is simple, the process is ingenious, the required instruments are highly popular, easy to popularize, and meet the high-efficiency detection requirements of new benzodiazepines. |
| priorityDate | 2022-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.