http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114410756-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2db76bcdf406c52f94b9d87cb1613d27 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6851 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6876 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6851 |
| filingDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4820ab7a75b5bf8f8efaef88026e751 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bdbf9af5a285173c0388f70a6b5c6ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb7250d8a92895f05f0309c963741b6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37398c87d5d9e5995e0217a1cae193bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc7586a98e04ebe41d183aa93f89f22a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_994d730f1c52abae9987379d7d8042e7 |
| publicationDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114410756-A |
| titleOfInvention | Reagent and kit for detecting single nucleotide polymorphism of cyp2c19 x 3 gene and application |
| abstract | The invention belongs to the technical field of gene detection, and discloses a reagent for detecting single nucleotide polymorphism of cyp2c19 x 3 gene, a kit and application. The reagent, comprising: a probe for detecting the cyp2c19 x 3 gene and/or a primer pair for amplifying the cyp2c19 x 3 gene; wherein, the bases at 1 or more positions in the probe for detecting the cyp2C19 x 3 gene are modified by locked nucleic acid, and methylene bridges formed by different glycidyl actions at 2 '-O, 4' -C positions of the locked nucleic acid form a rigid condensation structure, so that the stability of the local structure of the phosphate skeleton of the nucleic acid is improved; meanwhile, when the nucleic acid modified by the locked nucleic acid is applied to the detection of the fluorescent quantitative PCR probe, the annealing temperature of the detection reaction can be effectively increased, the length of the probe required by the detection can be shortened, and the probe has the advantages of higher sensitivity, stronger specificity and the like compared with the common probe. |
| priorityDate | 2021-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.