| abstract |
The application of the nucleic acid aptamer of the novel coronavirus S protein and the nucleic acid aptamer of the human ACE2 protein of the present invention provides the S1 subunit (referred to as the S1 protein for short) of the spike protein of the novel coronavirus (SARS-CoV-2). ) nucleic acid aptamer APT-S, and nucleic acid aptamer APT-A binding human ACE2 protein, and the purposes of these nucleic acid aptamers. Specifically, the nucleic acid aptamer and its derivatives of the present invention have the advantages of rapid chemical synthesis, small molecular weight, stability, easy storage and labeling, etc., and can be used in detection, diagnosis, imaging, and treatment applications. |