Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d8cce4d3d4443974c432ba754be4d473 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-011 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 |
filingDate |
2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c698d1ac890a4f955f5c08cd65cfcb65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0880bfc36869a9666db69be9ad54fa06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bf854c837754435914e0c805f31dd46 |
publicationDate |
2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-114404561-A |
titleOfInvention |
A protective agent for reducing vascular endothelial function damage |
abstract |
The invention provides a protective agent for reducing vascular endothelial function damage, belonging to the technical field of biomedicine. The active ingredient of the protective agent provided by the present invention is barnacle peptide. After using the barnacle peptide provided by the present invention to treat human umbilical vein endothelial cells, it can effectively reverse the decrease in cell viability caused by cholesterol, and can effectively reduce cholesterol The resulting up-regulation of the pro-apoptotic protein BAX and the down-regulation of the anti-apoptotic protein BCL-2 caused by elevated cholesterol. |
priorityDate |
2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |