http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114397278-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f2b9238405a6767aedf5eb684755a82 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-554 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-552 |
| filingDate | 2021-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9917d49e1aa5b69916eea872608d4d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_269fac13bef507ec33b161cb996dd20a |
| publicationDate | 2022-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114397278-A |
| titleOfInvention | Nanoparticle substrate for in-situ plasma resonance, preparation method thereof and application thereof in specificity detection |
| abstract | The invention discloses a nano-particle substrate for in-situ plasma resonance, a preparation method thereof and application thereof in specificity detection, wherein the preparation method of the nano-particle substrate for in-situ plasma resonance comprises the following steps: fixing a grid structure above the substrate, evaporating an adhesive layer on the substrate through the grid structure, depositing silver, copper or gold nanoparticles on the adhesive layer, separating the grid structure from the substrate, removing unstable nanoparticles on the surface of the substrate by using acetone, and drying by blowing to obtain the nanoparticle substrate for in-situ plasma resonance. The nanoparticles on the nanoparticle substrate are reduced using tris (2-carboxyethyl) phosphorus, thereby allowing the nanoparticles to specifically bind to thiol-modified aptamers, antibodies, or antigens for the detection of targets. The dark field scattering intensity of the nanoparticles, when bound to a specific target, is enhanced or red-shifted by the dark field scattering resonance peak. The nano-particles prepared by the invention have obvious plasma resonance peak and are suitable for specificity detection. |
| priorityDate | 2021-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.