http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114384240-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e2efaa482535230172df5e863f36c00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54313 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54386 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-33 |
| filingDate | 2021-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c63de0d5b3eee428591cb785a74f7ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17828fc097213b9f71f60bf01e856fe4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3f19fd792c73acb48f326593c8aaccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53fdeaee7c3d6e95c5e5fbb7b62dc7f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caec2abed05ea3fd569c423c49ef3a04 |
| publicationDate | 2022-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-114384240-A |
| titleOfInvention | Multi-target object simultaneous detection method based on latex microsphere ultraviolet absorption spectrum peak area integral |
| abstract | The invention discloses a method for simultaneously detecting multiple targets based on latex microsphere ultraviolet absorption spectrum peak area integral, wherein nano magnetic particles are magnetic separation carriers, and biological recognition molecules A corresponding to different targets are coupled on the surfaces of the nano magnetic particles and are respectively used as immune magnetic particles; coupling corresponding biological recognition molecules B on the surface of the latex microspheres serving as signal probes; carrying out sufficient immunoreaction on the immunomagnetic particles, the signal probe and a target object to be detected to obtain a mixed solution; and magnetic separation, namely, scanning the signal probe solution which does not participate in the reaction at the full wavelength, and selecting a corresponding wavelength range to perform peak area integration. The invention not only obviously improves the sensitivity and the accuracy, but also can realize the accurate analysis and quantification of each signal probe only by carrying out peak area integration on the ultraviolet absorption spectrum in a specific range. For substances with higher analysis sensitivity requirements, a plurality of click reactions are adopted to further amplify optical signals, and the dosage of a click reagent is optimized to achieve the purpose of simultaneously amplifying a plurality of target object signals. |
| priorityDate | 2021-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.