abstract |
The invention belongs to the technical field of medicine, discloses the preparation and use of neolignans in Angelica sinensis, and specifically relates to the remarkable sedative and hypnotic effects of new neolignans compounds. The results of animal experiments proved that compounds (+)‑1 and (‑)‑1 have obvious sedative and hypnotic effects, and are expected to be therapeutic drugs for mental diseases related to insomnia, convulsions, epilepsy/anxiety and depression. |